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CEM微波合成用于Racemization的研究
点击次数:947 发布时间:2012-06-29

INTRODUCTION

One potential issue in peptide synthesis is racemization of cysteine and histidine. This is a concern for microwave peptide syntheis because of the elevated temperatures during deprotection and coupling. Studies have shown that lowering the temperature to 50 °C during the coupling of histidine and cysteine will decrease racemization.

 
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