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CEM微波合成用于Racemization的研究

 更新时间:2012-06-29 点击量:1570

INTRODUCTION

One potential issue in peptide synthesis is racemization of cysteine and histidine. This is a concern for microwave peptide syntheis because of the elevated temperatures during deprotection and coupling. Studies have shown that lowering the temperature to 50 °C during the coupling of histidine and cysteine will decrease racemization.

 
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